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Article

Modeling sequence-sequence interactions for drug response.

Bioinformatics (Oxford, England) - 15 May 2007

Lin Min, Li Hongying, Hou Wei, Johnson Julie A, Wu Rongling

Abstract excerpt

MOTIVATION: Genetic interactions or epistasis may play an important role in the genetic etiology of drug response. With the availability of large-scale, high-density single nucleotide polymorphism markers, a great challenge is how to associate haplotype structures and complex drug response through its underlying pharmacodynamic mechanisms. RESULTS: We have derived a general statistical model for detecting an...

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PMID: 17392331
DOI: 10.1093/bioinformatics/btm110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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