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Article

Theoretical basis for the identification of allelic variants that encode drug efficacy and toxicity.

Genetics - 1 Jun 2005

Lin Min, Wu Rongling

Abstract excerpt

Almost all drugs that produce a favorable response (efficacy) may also produce adverse effects (toxicity). The relative strengths of drug efficacy and toxicity that vary in human populations are controlled by the combined influences of multiple genes and environmental influences. Genetic mapping has proven to be a powerful tool for detecting and identifying specific DNA sequence variants on the basis of the...

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Identifiers

PMID: 15802521
DOI: 10.1534/genetics.104.039958
PMCID: PMC1450425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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