Article
The future of pharmacogenetics in the treatment of heart failure.
Pharmacogenomics - 1 Nov 2015
Anwar Mohamed Subhan, Iskandar Muhammad Zaid, Parry Helen M, Doney Alex S, Palmer Colin N, Lang Chim C
Abstract excerpt
Heart failure is a common disease with high levels of morbidity and mortality. Current treatment comprises β-blockers, ACE inhibitors, aldosterone antagonists and diuretics. Variation in clinical response seen in patients begs the question of whether there is a pharmacogenetic component yet to be identified. To date, the genes most studied involve the β-1, β-2, α-2 adrenergic receptors and the...
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