The relative power of SNPs and haplotype as genetic markers for association tests.

doi:10.1517/14622416.2.1.11

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Article

The relative power of SNPs and haplotype as genetic markers for association tests.

Pharmacogenomics - 1 Feb 2001

Bader J S

Abstract excerpt

Identifying the polymorphisms that contribute to disease predisposition and drug response is a major goal of the post-genome era. Single nucleotide polymorphisms (SNPs) in disease-related genes are often used as candidates in the search for causative variations. Association tests based on haplotypes have also been suggested and, at times, have provided greater statistical power than tests based on the underlying...

Topics

Analysis of Variance
Genetic Diseases, Inborn
Genetic Markers
Genetic Predisposition to Disease
Genetic Variation
Genetics, Population
Genome, Human
Haplotypes
Humans
Linkage Disequilibrium
Models, Genetic
Pharmacogenetics
Polymorphism, Single Nucleotide
Quantitative Trait, Heritable
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 11258193
DOI: 10.1517/14622416.2.1.11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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