Article
Sequencing drug response with HapMap.
The pharmacogenomics journal - 1 Jan 2005
Lin M, Aquilante C, Johnson J A, Wu R
Abstract excerpt
The information about how DNA sequence varies across the human genome is crucial for unravelling the genetic basis of drug response. A haplotype map, or HapMap, intended to reveal such a variation pattern, has been recently developed by the International HapMap Consortium. Here, we present a conceptual model for directly characterizing specific DNA sequence variants that are responsible for drug response based on...
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