Article
Pharmacogenomics of adrenoceptors.
Pharmacogenomics - 1 Oct 2004
Flordellis C, Paris H, Karabinis A, Lymperopoulos A
Abstract excerpt
Adrenoceptors (ARs) consist of nine subtypes (alpha(1A)-, alpha(1B)-, alpha(1D)-, beta(1)-, beta(2)-, beta(3)-, alpha(2A)-, alpha(2B)- and alpha(2C)-AR), which are involved in a wide spectrum of physiological functions and are the site of action for a considerable percentage of currently prescribed therapeutics. With the exception of alpha(1D), all AR subtypes are polymorphic with genetic variations in the coding...
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