Article

Characterizing the genetic architecture of drug response using gene-context interaction methods

2024-03-30

Abstract excerpt

Identifying the factors responsible for variability of treatment response is a central objective of clinical research. Specially designed pharmacogenomic studies have identified a handful of individual mutations modulating the effect of specific drugs. However, the extent to which drug response variability is driven by genetics is largely unknown, partly due to the small sample sizes of prospective pharmacogenomic...

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Literature Corpus work: 29098c57-a5c0-558e-a38d-b8cb1b26c578
DOI: 10.1101/2024.03.29.24305093

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