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Article

Lead and delta-aminolevulinic acid dehydratase polymorphism: where does it lead? A meta-analysis.

Environmental health perspectives - 1 Jan 2007

Scinicariello Franco, Murray H Edward, Moffett Daphne B, Abadin Henry G, Sexton Mary J, Fowler Bruce A

Abstract excerpt

BACKGROUND: Lead poisoning affects many organs in the body. Lead inhibits delta-aminolevulinic acid dehydratase (ALAD), an enzyme with two co-dominantly expressed alleles, ALAD1 and ALAD2. OBJECTIVE: Our meta-analysis studied the effects of the ALAD polymorphism on a) blood and bone lead levels and b) indicators of target organ toxicity. DATA SOURCE: We included studies reporting one or more of the following by...

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Identifiers

PMID: 17366816
DOI: 10.1289/ehp.9448
PMCID: PMC1797830

Genes

ALAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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