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Article

Use of Generalized Additive Model to Detect the Threshold of δ-Aminolevulinic Acid Dehydratase Activity Reduced by Lead Exposure.

International journal of environmental research and public health - 7 Aug 2020

Huang Chan-Ching, Yang Chen-Cheng, Liu Te-Yu, Dai Chia-Yen, Wang Chao-Ling, Chuang Hung-Yi

Abstract excerpt

BACKGROUND: Lead inhibits the enzymes in heme biosynthesis, mainly reducing δ-aminolevulinic acid dehydratase (ALAD) activity, which could be an available biomarker. The aim of this study was to detect the threshold of δ-aminolevulinic acid dehydratase activity reduced by lead exposure. METHODS: We collected data on 121 lead workers and 117 non-exposed workers when annual health examinations were performed. ALAD...

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Identifiers

PMID: 32784669
DOI: 10.3390/ijerph17165712
PMCID: PMC7460038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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