Article
Relationship between delta-aminolevulinic acid dehydratase genotypes and heme precursors in lead workers.
American journal of industrial medicine - 1 Sept 2000
Sakai T, Morita Y, Araki T, Kano M, Yoshida T
Abstract excerpt
BACKGROUND: The objective of this study was to investigate the relationships between genotypes of delta-aminolevulinic acid (ALA) dehydratase (ALAD) and disturbances in the heme biosynthetic pathway by lead exposure. METHODS: The subjects were 192 male lead workers and 125 control subjects. Blood lead concentrations (Pb-B), plasma ALA concentrations (ALA-P), and ALAD genotypes were determined for all subjects. In...
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