Article
Stability of p53 protein in rat cells transformed by various viral transforming genes.
Virology - 1 Mar 1992
Inoue H, Kondoh G, Sudiro T M, Hakura A
Abstract excerpt
To clarify the correlation between metabolic stabilization of p53 protein and cellular transformation, we transformed the normal rat cell line F2408 with various viral transforming genes and examined the expression and stability of p53 protein in these transformed cells by pulse-chase immunoprecipitation experiments. As expected, the level of p53 in the SV40-transformed rat cell line was higher than that in the...
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