Stability of p53 protein in rat cells transformed by various viral transforming genes.

doi:10.1016/0042-6822(92)90325-j

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Article

Stability of p53 protein in rat cells transformed by various viral transforming genes.

Virology - 1 Mar 1992

Inoue H, Kondoh G, Sudiro T M, Hakura A

Abstract excerpt

To clarify the correlation between metabolic stabilization of p53 protein and cellular transformation, we transformed the normal rat cell line F2408 with various viral transforming genes and examined the expression and stability of p53 protein in these transformed cells by pulse-chase immunopreci...

Topics

Animals
Cell Line
Cell Transformation, Viral
Gene Expression Regulation, Neoplastic
Mutation
Oncogenes
Precipitin Tests
Proto-Oncogenes
Rats
Tumor Suppressor Protein p53
Viral Plaque Assay

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