Altered phosphorylation at specific sites confers a mutant phenotype to SV40 wild-type large T antigen in a flat revertant of SV40-transformed cells.

Article

Altered phosphorylation at specific sites confers a mutant phenotype to SV40 wild-type large T antigen in a flat revertant of SV40-transformed cells.

Oncogene - 1 Oct 1991

Deppert W, Kurth M, Graessmann M, Graessmann A, Knippschild U

Abstract excerpt

The Rev2 cell line is a cellular revertant of the SV40 wild-type transformed rat cell line SV-52 [Bauer, M., Guhl, E., Graessmann, M. & Graessmann, A. (1987). J. Virol., 61, 1821-1827]. To characterize the level of cellular interference with the SV40 large T antigen (large T)-induced transformati...

Topics

Animals
Antigens, Polyomavirus Transforming
Cell Line, Transformed
DNA, Viral
Mutation
Phenotype
Phosphorylation
Rats
Tumor Suppressor Protein p53

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