Binding of cellular proteins to a conformational domain of tumor suppressor protein p53.

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Article

Binding of cellular proteins to a conformational domain of tumor suppressor protein p53.

Oncogene - 1 Dec 1993

Maxwell S A, Roth J A

Abstract excerpt

The genes regulated by p53, as well as the factors modulating its function, need to be identified before the mechanism of action of p53 in control of cell growth can be adequately understood. Binding of the SV40 large T-antigen protein to an evolutionally conserved (conformational) domain of p53...

Topics

Antigens, Polyomavirus Transforming
Binding, Competitive
Carcinoma, Non-Small-Cell Lung
Carrier Proteins
Cell Division
Humans
Lung Neoplasms
Molecular Weight
Mutation
Osteosarcoma
Protein Binding
Protein Conformation
Proteins
Tumor Cells, Cultured
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 8247546

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8247546-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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