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Article

Correlation of metabolic stability and altered quaternary structure of oncoprotein p53 with cell transformation.

Experimental cell research - 1 Jan 1991

Kraiss S, Spiess S, Reihsaus E, Montenarh M

Abstract excerpt

The phosphoprotein p53 seems to be implicated in various processes connected with cell transformation and in particular with the regulation of cell cycle and probably DNA replication. In the present paper we have analyzed two sets of closely related cell lines expressing the same p53 which exhibited either a nontransformed or a transformed phenotype. These cell lines were used to study biochemical properties of...

Topics

Animals
Cell Line
Cell Line, Transformed
Cell Transformation, Neoplastic
Macromolecular Substances
Phenotype
Tumor Suppressor Protein p53

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1984409
DOI: 10.1016/0014-4827(91)90170-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1984409-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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