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Article

Regulation of the level of the oncoprotein p53 in non-transformed and transformed cells.

Oncogene - 1 Jan 1990

Reihsaus E, Kohler M, Kraiss S, Oren M, Montenarh M

Abstract excerpt

In order to contribute to the understanding of the activation of the oncoprotein p53 we determined the metabolic stability of p53 in a variety of non-transformed, immortalized and SV40- and non-SV40-transformed cell lines. In addition, we analyzed the metabolic stability of the SV40 large T antigen in SV40 transformed cell lines. Pulse-chase experiments revealed a low stability (t1/2 = 20 min) of p53 in...

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Source

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PMID: 2157179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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