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Article

The properties of p53 proteins selected for the loss of suppression of transformation.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jan 1994

Olson D C, Levine A J

Abstract excerpt

The wild-type p53 protein can act as a suppressor of transformation in that it will block or reduce the formation of adenovirus E1A plus ras mediated transformants of primary rat embryo fibroblasts (C. A. Finlay et al., Cell, 57: 1083-1093, 1989). In those experiments, all of the transformed cell lines that arose selected for mutations in the transfected p53 gene, and many of these cell lines now express mutant...

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PMID: 8123594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The properties of p53 proteins selected for the loss of suppression of transformation.PMID 8123594Read ↗

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