Article
Transient stabilization of p53 in non-small cell lung carcinoma cultures arrested for growth by retinoic acid.
Experimental cell research - 1 Sept 1994
Maxwell S A, Mukhopadhyay T
Abstract excerpt
Proliferation of five non-small cell lung carcinoma (NSCLC) cultures was inhibited after 16 h exposure to retinoic acid. We investigated whether expression of the p53 protein correlated with the growth pattern of NSCLC lines observed in the presence of retinoic acid Levels of wild-type p53 protein underwent fivefold increases in lines H460a and H226b after 16 to 48 h treatment with 5 microM retinoic acid but then...
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