Article
Structural polymorphism of the actin-espin system: a prototypical system of filaments and linkers in stereocilia.
Physical review letters - 2 Feb 2007
Purdy Kirstin R, Bartles James R, Wong Gerard C L
Abstract excerpt
We examine the interaction between cytoskeletal F-actin and espin 3A, a prototypical actin bundling protein found in sensory cell microvilli, including ear cell stereocilia. Espin induces twist distortions in F-actin as well as facilitates bundle formation. Mutations in one of the two F-actin bin...
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