Article
A Biophysical Model for the Staircase Geometry of Stereocilia.
PloS one - 1 Jan 2015
Orly Gilad, Manor Uri, Gov Nir S
Abstract excerpt
Cochlear hair cell bundles, made up of 10s to 100s of individual stereocilia, are essential for hearing, and even relatively minor structural changes, due to mutations or injuries, can result in total deafness. Consistent with its specialized role, the staircase geometry (SCG) of hair cell bundles presents one of the most striking, intricate, and precise organizations of actin-based cellular shapes. Composed of...
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