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Article

Actin in hair cells and hearing loss.

Hearing research - 1 Jun 2012

Drummond Meghan C, Belyantseva Inna A, Friderici Karen H, Friedman Thomas B

Abstract excerpt

Hereditary deafness is genetically heterogeneous such that mutations of many different genes can cause hearing loss. This review focuses on the evidence and implications that several of these deafness genes encode actin-interacting proteins or actin itself. There is a growing appreciation of the contribution of the actin interactome in stereocilia development, maintenance, mechanotransduction and malfunction of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22200607
DOI: 10.1016/j.heares.2011.12.003
PMCID: PMC3403717

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