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Article

Long isoforms of Espin and Espin-Like proteins are essential for development and maintenance of mechanotransducing stereocilia.

Molecular biology of the cell - 1 Aug 2026

Hawbaker Katelin M, Joshi Priyanka, Liao Xiayi, Tung Chun-Yu, Perrin Benjamin J

Abstract excerpt

Stereocilia are giant, specialized microvilli on auditory sensory cells in the inner ear. Their precise size and tiered organization are essential for function and are strictly controlled by actin-regulating proteins during postnatal development. Among these proteins, Espins (ESPNs) and Espin-like (ESPNL) proteins contribute to normal stereocilia development; however, the potential overlapping function between...

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Share to Hair Cells, Auditory
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42160510
DOI: 10.1091/mbc.E25-07-0360
PMCID: PMC13428342

Genes

ESPNL
ESPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Long isoforms of Espin and Espin-Like proteins are essential for development and maintenance of mechanotransducing stereocilia.PMID 42160510Read ↗

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