Article
Recessive expression of the H2A-controlled immune response phenotype depends critically on antigen dose.
Immunology - 1 Feb 2000
Barcenas-Morales G, Merkenschlager M, Wahid F, Döffinger R, Ivanyi J
Abstract excerpt
Major histocompatibility complex (MHC) alleles acting as immune response genes are coexpressed in heterozygous individuals and therefore control of immune responses is usually codominant. As an exception to this rule, however, several examples of recessive immune responses have been ascribed to regulatory, e.g. suppressive, interactions. We report here that the recessive phenotype of both antibody and T-cell...
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