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Article

Hemopoietic histocompatibility (Hh-1) regulatory and structural genes of the f haplotype map to H-2.

Transplantation - 1 Mar 1990

Rembecki R M, Kumar V, David C S, Bennett M

Abstract excerpt

Natural resistance to bone marrow stem cell (BMC) grafts in lethally irradiated mice is a consequence of natural killer cell recognition and elimination of BMC that express hemopoietic histocompatibility (Hh) antigens inherited noncodominantly. The major Hh genetic region, Hh-1, maps to H-2. The phenotype of the BMC was determined by grafting BMC into panels of irradiated mice, and measuring splenic incorporation...

Topics

Animals
Bone Marrow Transplantation
Chromosome Mapping
Gene Expression
Genes
Genes, Regulator
H-2 Antigens
Haplotypes
Hematopoietic Stem Cells
Histocompatibility Antigens
Major Histocompatibility Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred Strains

Phenotype

Recombination, Genetic

Source

Identifiers

PMID: 2316021
DOI: 10.1097/00007890-199003000-00030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2316021-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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