Association of H2Ab with resistance to collagen-induced arthritis in H2-recombinant mouse strains: an allele associated with reduction of several apparently unrelated responses.

doi:10.1007/BF00172065

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Article

Association of H2Ab with resistance to collagen-induced arthritis in H2-recombinant mouse strains: an allele associated with reduction of several apparently unrelated responses.

Immunogenetics - 1 Jan 1995

Mitchison N A, Brunner M C

Abstract excerpt

HLA class II alleles can protect against immunological diseases. Seeking an animal model for a naturally occurring protective allele, we screened a panel of H2-congenic and recombinant mouse strains for ability to protect against collagen-induced arthritis. The strains were crossed with the susce...

Topics

Alleles
Animals
Arthritis
Collagen
H-2 Antigens
Immunity, Innate
Mice
Recombination, Genetic

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