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Article

HDAC2 controls IgM H- and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Mar 2007

Nakayama Masami, Suzuki Hiroyuki, Yamamoto-Nagamatsu Nahoko, Barman Hirak Kumar, Kikuchi Hidehiko, Takami Yasunari, Toyonaga Kenji, Yamashita Koki, Nakayama Tatsuo

Abstract excerpt

We previously reported that histone deacetylase-2 (HDAC2) controls the amount of IgM H-chain at the steps of transcription of its gene and alternative processing of its pre-mRNA in DT40 cells. Here, we showed not only that the HDAC2-deficiency caused repressions of gene expressions for HDAC7, EBF1, Pax5, Aiolos and Ikaros, and elevations of gene expressions for HDAC4, HDAC5, PCAF and E2A, but also that it caused...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Ikaros Transcription Factor

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Source

Identifiers

PMID: 17352740
DOI: 10.1111/j.1365-2443.2007.01059.x

Genes

EBF1
HDAC2
HDAC4
HDAC5
HDAC7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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