Article
Histone H1 variants play individual roles in transcription regulation in the DT40 chicken B cell line.
Biochemical and biophysical research communications - 16 Feb 2000
Takami Y, Nishi R, Nakayama T
Abstract excerpt
Thirty-nine of the 44 chicken histone genes are located in a major gene cluster of 110 kb, the others being distributed in four separate regions. All 6 H1 genes, which are present in the cluster and encode different variants, are expressed in the DT40 chicken B cell line, at levels ranging from about 5 to 40%. To clarify differences in the natures of these H1 variants, using gene-targeting techniques, we...
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