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Article

Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression.

Genes & development - 1 Mar 2010

Yamaguchi Teppei, Cubizolles Fabien, Zhang Yu, Reichert Nina, Kohler Hubertus, Seiser Christian, Matthias Patrick

Abstract excerpt

Histone deacetylases (HDACs) regulate gene expression by deacetylating histones and also modulate the acetylation of a number of nonhistone proteins, thus impinging on various cellular processes. Here, we analyzed the major class I enzymes HDAC1 and HDAC2 in primary mouse fibroblasts and in the B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20194438
DOI: 10.1101/gad.552310
PMCID: PMC2827841

Genes

HDAC1
HDAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20194438-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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