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Article

A novel locus affecting serum levels of IgG2a maps to the murine H2 region.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jun 2000

Matthews V B, Christiansen F T, Price P

Abstract excerpt

The effects of genes in the murine H2 region on basal immunoglobulin levels were investigated and ratios of IgG1/IgG2a were calculated, as low ratios indicate a Th1 cytokine mileu. H2b mice with B10 or BALB genetic backgrounds had higher levels of IgG2a than H2k and H2d congenic strains, and hence had low IgG1/IgG2a ratios. B10 (H2b) mice generally had high levels of IgG2b, IgG3, IgA and IgM, but this outcome was...

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Identifiers

PMID: 10940081
DOI: 10.1046/j.1365-2370.2000.00216.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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