Article
Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.
Pharmacogenetics - 1 Apr 2002
Lee Craig R, Goldstein Joyce A, Pieper John A
Abstract excerpt
The discovery of six distinct polymorphisms in the genetic sequence encoding for the cytochrome P450 2C9 (CYP2C9) protein has stimulated numerous investigations in an attempt to characterize their population distribution and metabolic activity. Since the CYP2C9*1, *2 and *3 alleles were discovered first, they have undergone more thorough investigation than the recently identified *4, *5 and *6 alleles. Population...
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