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Article

Prevalence of CCR5Delta32 polymorphism in long-term survivors of heart transplantation.

Transplant immunology - 1 Apr 2007

Hummel Manfred, Bara Christoph, Hirt Stephan, Haverich Axel, Hetzer Roland

Abstract excerpt

BACKGROUND: CC chemokine receptor 5 (CCR5) contributes to the alloimmune response following solid organ transplantation. In individuals homozygous for the CCR5Delta32 mutation, the receptor is inactive and lymphocyte recruitment and leukocyte trafficking during rejection are inhibited. A significant improvement in graft survival following renal transplantation has been observed in homozygous CCR5Delta32 patients,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17331851
DOI: 10.1016/j.trim.2006.11.004

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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