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Article

CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual.

PloS one - 23 Jul 2008

Oh Djin-Ye, Jessen Heiko, Kücherer Claudia, Neumann Konrad, Oh Nari, Poggensee Gabriele, Bartmeyer Barbara, Jessen Arne, Pruss Axel, Schumann Ralf R, Hamouda Osamah

Abstract excerpt

BACKGROUND: Homozygosity (Delta32/Delta32) for the 32 bp deletion in the chemokine receptor 5 (CCR5) gene is associated with strong resistance against HIV infection. Heterozygosity is associated with protection of HIV-1 disease progression. METHODOLOGY/PRINCIPAL FINDINGS: We genotyped a population of 737 HIV-positive adults and 463 healthy controls for the CCR5Delta32 deletion and found heterozygous frequencies...

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Identifiers

PMID: 18648518
DOI: 10.1371/journal.pone.0002747
PMCID: PMC2453227

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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