Article
Lack of higher frequency of the chemokine receptor 5-delta32/delta32 genotype in hepatitis C.
Journal of clinical gastroenterology - 1 Jan 2000
Tommasi Anna Maria, Fabris Paolo, Carderi Isabella, Baragiotta Anna, Baldo Vincenzo, Venturi Carla, Giordani Maria Teresa, Tositti Giulia, Floreani Annarosa
Abstract excerpt
PURPOSE: An elevated frequency of the CCR5-Delta32 mutation in German patients with hepatitis C with viremia has been reported. The aim of the present study was to verify whether this mutation occurs in an Italian population with hepatitis C and whether it is an adverse host factor indicative of severity of liver disease and response to antiviral therapy. STUDY: The authors amplified 189-bp (wild-type) and 157-bp...
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