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Article

Donor CCR5 Delta32 polymorphism and outcome following cardiac transplantation.

Transplantation proceedings - 1 Jun 2005

Fildes J E, Walker A H, Howlett R, Bittar M N, Hutchinson I V, Leonard C T, Yonan N

Abstract excerpt

BACKGROUND: Chemokines regulate the recruitment and trafficking of leukocytes during an immune response. Animal models have shown correlations between chemokine production and leukocyte infiltration during allograft rejection. Also, antagonism of chemokine receptors in transplant models has produced prolonged graft survival. Individuals homozygous for a 32 base pair deletion in the CC chemokine receptor 5 (CCR5)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15964389
DOI: 10.1016/j.transproceed.2005.03.101

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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