Article
CC chemokine receptor 5 delta32 polymorphism in two independent cohorts of hepatitis C virus infected patients without hemophilia.
Journal of molecular medicine (Berlin, Germany) - 1 Jan 2004
Wasmuth Hermann E, Werth Alexa, Mueller Tobias, Berg Thomas, Dietrich Christoph G, Geier Andreas, Schirin-Sokhan Ramin, Gartung Carsten, Lorenzen Johann, Matern Siegfried, Lammert Frank
Abstract excerpt
Recently CC chemokine receptor 5 (CCR5) related immune mechanisms and a functional mutation of the CCR5 gene have been implicated in hepatitis C virus (HCV) infection in a cohort of predominantly hemophiliac patients. The present study investigated the frequency and clinical consequences of the CCR5 Delta32 mutation in two genetically homogeneous populations of HCV infected patients with a different risk profile...
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