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Article

Chemokine receptor 5Delta32 mutation reduces the risk of acute rejection in liver transplantation.

Annals of transplantation - 1 Jan 2000

Heidenhain Christoph, Puhl Gero, Moench Christian, Lautem Anja, Neuhaus Peter

Abstract excerpt

BACKGROUND: Chemokine receptor 5 (CCR-5) plays a central role in allograft rejection. CCR-5Delta32 mutation results in a non-functioning receptor. Homozygous CCR-5Delta32 patients show a significantly improved kidney graft survival rate compared to CCR-5 wild-type patients. Similar correlations between the CCR-5Delta32 genotype and acute rejection or graft survival rate were shown for heart, lung and islet cell...

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Source

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PMID: 19644158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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