Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of CCR5-Δ32 deletion on C-reactive protein levels and cardiovascular disease: Results from the Danish Blood Donor Study.

Atherosclerosis - 1 Sept 2015

Dinh Khoa M, Pedersen Ole B, Petersen Mikkel S, Sørensen Erik, Sørensen Cecilie J, Kaspersen Kathrine A, Larsen Margit H, Møller Bjarne, Hjalgrim Henrik, Ullum Henrik, Erikstrup Christian

Abstract excerpt

BACKGROUND AND PURPOSE: The C-C chemokine receptor 5-Δ32 deletion (CCR5-Δ32) has been associated with lower levels of C-reactive protein (CRP), but the effect on cardiovascular diseases is uncertain. This study addresses the impact of CCR5-Δ32 on the risk of low-grade inflammation and hospitalization with cardiovascular diseases in a large cohort of blood donors. METHODS: Genotyping of 15,206 healthy participants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Reactive Protein
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Denmark

Share to Gene Deletion

Share to Hospitalization

Share to Inflammation

Share to Receptors, CCR5

Share to Risk Assessment

Source

Identifiers

PMID: 26222902
DOI: 10.1016/j.atherosclerosis.2015.07.031

Genes

CCR5
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of CCR5-Δ32 deletion on C-reactive protein levels and cardiovascular disease: Results from the Danish Blood Donor Study.PMID 26222902Read ↗

CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study.Semantic proximity Read ↗

Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors.Semantic proximity Read ↗

Common CCR5-del32 Frameshift Mutation Associated With Serum Levels of Inflammatory Markers and Cardiovascular Disease Risk in the Bruneck PopulationSemantic proximity Read ↗

The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysms.Semantic proximity Read ↗

The effect of the CCR5-delta32 deletion on global gene expression considering immune response and inflammationSemantic proximity Read ↗

Genetic association of the CCR5 region with lipid levels in at-risk cardiovascular patients.Semantic proximity Read ↗

No statistical evidence for an effect of CCR5-∆32 on lifespan in the UK Biobank cohortSemantic proximity Read ↗

Distribution of the CCR5-delta32 deletion in Southwest Germany.Semantic proximity Read ↗

TNF-α levels are not increased in inflamed patients carrying the CCR5 deletion 32.Semantic proximity Read ↗

Effect of genetic variants of chemokine receptors on the development of myocardial infarction in Turkish population.Semantic proximity Read ↗

Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C.Semantic proximity Read ↗

CCR5Δ32 mutations do not determine COVID-19 disease course.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.