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Article

Clinical significance of the CCR5delta32 allele in hepatitis C.

PloS one - 1 Jan 2014

Morard Isabelle, Clément Sophie, Calmy Alexandra, Mangia Alessandra, Cerny Andrea, De Gottardi Andrea, Gorgievski Meri, Heim Markus, Malinverni Raffaele, Moradpour Darius, Müllhaupt Beat, Semela David, Pascarella Stéphanie, Bochud Pierre-Yves, Negro Franco

Abstract excerpt

BACKGROUND: The CCR5 receptor, expressed on Th1 cells, may influence clinical outcomes of HCV infection. We explored a possible link between a CCR5 32-base deletion (CCR5delta32), resulting in the expression of a non-functioning receptor, and clinical outcomes of HCV infection. METHODS: CCR5 and HCV-related phenotypes were analysed in 1,290 chronically infected patients and 160 patients with spontaneous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25191700
DOI: 10.1371/journal.pone.0106424
PMCID: PMC4156365

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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