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Article

Inactive X chromosome-specific reduction in placental DNA methylation

7 Jul 2009

Abstract excerpt

Genome-wide levels of DNA methylation vary between tissues, and compared with other tissues, the placenta has been reported to demonstrate a global decrease in methylation as well as decreased methylation of X-linked promoters. Methylation is one of many features that differentiate the active and inactive X, and it is well established that CpG island promoters on the inactive X are hypermethylated. We now report...

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PMID: 19586922
DOI: 10.1093/hmg/ddp299

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