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Article

Allele-specific non-CG DNA methylation marks domains of active chromatin in female mouse brain.

Proceedings of the National Academy of Sciences of the United States of America - 4 Apr 2017

Keown Christopher L, Berletch Joel B, Castanon Rosa, Nery Joseph R, Disteche Christine M, Ecker Joseph R, Mukamel Eran A

Abstract excerpt

DNA methylation at gene promoters in a CG context is associated with transcriptional repression, including at genes silenced on the inactive X chromosome in females. Non-CG methylation (mCH) is a distinct feature of the neuronal epigenome that is differentially distributed between males and females on the X chromosome. However, little is known about differences in mCH on the active (Xa) and inactive (Xi) X...

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Share to Chromatin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Genomic Imprinting

Share to Mice, Mutant Strains

Share to RNA, Long Noncoding

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Share to X Chromosome Inactivation

Source

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Identifiers

PMID: 28320934
DOI: 10.1073/pnas.1611905114
PMCID: PMC5389278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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