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Article

RILM: a web-based resource to aid comparative and functional analysis of the insulin and IGF-1 receptor family.

Human mutation - 1 Jul 2007

Garza-Garcia Acely, Patel Dhaval S, Gems David, Driscoll Paul C

Abstract excerpt

The metazoan receptors for insulin (INSR), insulin-like growth factor 1 (IGF1R), and other insulin-like molecules are transmembrane tyrosine kinases involved in the regulation of cell size, cell proliferation, development, signaling of nutritional and environmental conditions, and aging. Historically, mutations in the human insulin receptor have been studied because such changes often lead to severe insulin...

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Identifiers

PMID: 17318838
DOI: 10.1002/humu.20491
PMCID: PMC4335190

Genes

IGF1
INSR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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