Article
Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies
14 Feb 2007
Abstract excerpt
KIR3DL1 is one of the best-characterised inhibitory NK cell receptors. Unusually, one common allele at the 3DL1 locus encodes an activating receptor known as 3DS1. There is genetic evidence for a protective role of 3DS1 in certain viral diseases, but there has been uncertainty about expression of the 3DS1 protein. Using transfection, we show that surface expression of 3DS1 is reliant on the adaptor protein...
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