Article
Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation?
Journal of immunology (Baltimore, Md. : 1950) - 15 May 2008
Thomas Rasmi, Yamada Eriko, Alter Galit, Martin Maureen P, Bashirova Arman A, Norman Paul J, Altfeld Marcus, Parham Peter, Anderson Stephen K, McVicar Daniel W, Carrington Mary
Abstract excerpt
KIR3DL1 shows extensive polymorphism, and its variation has functional significance in terms of cell-surface expression levels and inhibitory capacity. We characterized nine KIR3DL1 alleles (*022, *028, *029, *033, *035, *051, *052, *053, and *054), four of which were identified for the first time in this study, and compared them to known alleles in phylogenetic analysis. Blood was available from eight...
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