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Article

Allelic diversity of KIR3DL1/3DS1 in a southern Chinese population.

Human immunology - 1 Sept 2015

Deng Zhihui, Zhen Jianxin, Zhu Bofeng, Zhang Guobing, Yu Qiong, Wang Daming, Xu Yunping, He Liumei, Lu Liang

Abstract excerpt

The inhibitory KIR3DL1 and the activating KIR3DS1 segregate as alleles of the same locus. KIR3DL1 is highly diversified at the allele level and KIR3DL1 alleles exhibit varied levels of expression and ligand binding affinity resulting in varied degrees of NK cell inhibition. Previous studies have shown that the KIR3DL1/3DS1 polymorphism associated with viral infection, cancer and transplantation. However, little...

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Source

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PMID: 26416088
DOI: 10.1016/j.humimm.2015.09.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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