Article
Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2001
Gardiner C M, Guethlein L A, Shilling H G, Pando M, Carr W H, Rajalingam R, Vilches C, Parham P
Abstract excerpt
KIR3DL1 and KIR3DL2 are NK cell receptors for polymorphic HLA-B and -A determinants. The proportion of NK cells that bind anti-KIR3DL1-specific Ab DX9 and their level of binding vary between individuals. To determine whether these differences are due to KIR polymorphism, we assessed KIR3D gene di...
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