Article
TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease.
Disease markers - 1 Jan 2006
Puthothu Beena, Forster Johannes, Heinzmann Andrea, Krueger Marcus
Abstract excerpt
Respiratory syncytial virus (RSV) is the most common viral respiratory pathogen during infancy world wide. It induces innate and adaptive immune response in host cells. The toll like receptor 4 (TLR4)/CD14 complex is particularly important for the initiation of an innate immune response to RSV. Thus we were interested whether an association exists between severe RSV associated diseases and polymorphisms within...
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