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Article

Association between Severe Respiratory Syncytial Virus Infection andIL13/IL4Haplotypes

3 Jan 2006

Abstract excerpt

Respiratory syncytial virus (RSV) infection has been implicated in the pathogenesis of bronchial asthma. In both diseases, interleukin (IL)-4 and IL-13 play important roles. By investigating IL4 and IL13 polymorphisms in 131 children with severe RSV infection and 270 control subjects, we found an association between IL13 polymorphism -1112C/T and severe RSV infection (P = .026). Furthermore, certain haplotypes...

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PMID: 16388492
DOI: 10.1086/499316

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