Article
Assessment of genetic associations between common single nucleotide polymorphisms in RIG-I-like receptor and IL-4 signaling genes and severe respiratory syncytial virus infection in children: a candidate gene case-control study.
PloS one - 1 Jan 2014
Marr Nico, Hirschfeld Aaron F, Lam Angie, Wang Shirley, Lavoie Pascal M, Turvey Stuart E
Abstract excerpt
The majority of cases of severe pediatric respiratory syncytial virus (RSV) infection occur in otherwise healthy infants who have no identifiable risk factors, suggesting that additional subclinical factors, such as population genetic variation, influence the course of RSV infection. The objective of this study was to test if common single nucleotide polymorphisms (SNPs) in genes encoding for immune signalling...
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