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Article

Respiratory syncytial virus infection and recurrent wheezing in Chilean infants: a genetic background?

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2013

Tapia Lorena I, Ampuero Sandra, Palomino M Angélica, Luchsinger Vivian, Aguilar Nelson, Ayarza Eliana, Mamani Rossana, Larrañaga Carmen

Abstract excerpt

UNLABELLED: Respiratory syncytial virus (RSV) infection has been associated to recurrent wheezing, but pathogenic mechanisms are unclear. Interleukin-4/Interleukin-13 (IL-4/IL-13) pathway is involved in both conditions. A common host genetic susceptibility may exist in patients whom RSV will trigger severe illness and those who develop recurrent wheezing. OBJECTIVE: To assess, by a candidate-gene approach,...

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PMID: 23333336
DOI: 10.1016/j.meegid.2012.12.030

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