Article
The role of TLR4 and CD14 polymorphisms in the pathogenesis of respiratory syncytial virus bronchiolitis in greek infants.
International journal of immunopathology and pharmacology - 1 Jan 2000
Goutaki M, Haidopoulou K, Pappa S, Tsakiridis P, Frydas E, Eboriadou M, Hatzistylianou M
Abstract excerpt
Clinical manifestations of respiratory syncytial virus (RSV) infection vary from minimal disease to severe acute bronchiolitis. The structural complex of TLR4/CD14 participates in the virus recognition as a component of natural immune response. Genetic variations of TLR4/CD14 may explain great variations in disease severity. The aim of this study was to investigate the possible role of polymorphisms of TLR4,...
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