Article
Immunohistochemical and mutational analysis of apoptosis-inducing factor (AIF) in colorectal carcinomas.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Dec 2006
Jeong Eun Goo, Lee Jong Woo, Soung Young Hwa, Nam Suk Woo, Kim Sang Ho, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung
Abstract excerpt
Apoptosis-inducing factor (AIF) has a principal role in caspase-independent apoptosis. In addition, AIF has a vital oxidoreductase activity that is required for cell survival. It may be important to identify the alterations of the AIF gene and AIF protein expression to see the function of AIF in human cancers. In this study we analyzed the expression of AIF protein in 103 colorectal carcinomas by...
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